For its treatment, adults are treated using an adequate amount of fluconazole on a daily basis, which is normally administered through IV. Nevertheless, echinocandid and lipid formulation amphoteric B are the most efficient for treating critically-ill patients. The neutropenic patients, on the other hand, are treated using Amphoteric B and echinoacids. Research has shown that though patients may register the same level of infection clearance, treatment with a low-dose result in 40 percent less side-effects as compared to high dosages. However, Flucanozole causes the least side effects as compared to all other forms of treatment.
Epidemiology and Prevention
For the effective prevention measures to be devices, the understanding of the pathegonecity of mechanisms is necessary. The antifungal drugs are designed to attach the activities of the fungus on the organisms; however, recently, scientists can target the virulence factors to get to the actual fungus. However, prevention is better than cure, therefore, a number of prevention measures have been devised. Keeping a healthy lifestyle is key to preventing invasion by fungal infections. In addition, good hygiene, careful use of antibiotics and proper nutrition can prevent the growth of the fungus. However, in the case of individuals with weakened immunity (for example, HIV, cancer, transplant, and ICU patients) could use anti-fungal drugs in advance to prevent the infections.
Conclusion
Clearly, the fungal infection ought to be taken seriously. The fact that it exists in a in an normal adult should not alarm people since fungus exist normally in bodies. However, a number of factors (virulence factors) have been noted to cause the infection. Other than highlighting its diagnosis and treatment options, this article has also noted the prevention measures that ought to be carried out.
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Bibliography
Calderone, Richard A., and William A. Fonzi. "Virulence factors of Candida albicans." Trends in microbiology 9, no. 7 (2001): 327-335.
Gow, Neil AR, Frank L. Van De Veerdonk, Alistair JP Brown, and Mihai G. Netea. "Candida albicans morphogenesis and host defence: discriminating invasion from colonization." Nature Reviews Microbiology 10, no. 2 (2011): nrmicro2711.
Mayer, Francois L., Duncan Wilson, and Bernhard Hube. "Candida albicans pathogenicity mechanisms." Virulence 4, no. 2 (2013): 119-128.
Sudbery, Peter E. "Growth of Candida albicans hyphae." Nature Reviews Microbiology 9, no. 10 (2011): 737-748.
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